Leo discovers three teen super-humans Adam, Bree and Chase, living in a secret underground lab in the high-tech home he shares with his inventor stepdad, Donald Davenport, his mom, Tasha, and Eddy, the "smart house" computer. Leo takes the trio to school, but when they are unable to contain their bionic abilities on campus, Davenport sends them away to a remote secret lab.
Leo is an ordinary teenager who has moved into a high-tech "smart'' house with his mother, inventor stepfather and Eddy, the computer that runs the house. Leo's life becomes less ordinary when, one day, he discovers a secret underground lab that houses three experiments: superhuman teenagers. The trio -- Adam, the strong one, Bree, the fast one and Chase, the smart one -- convinces Leo and his parents to let them leave their lab and join Leo at school, where they try to fit in while having to manage their unpredictable bionic strengths. As Leo figures out a way to keep his new pals' bionic abilities a secret, they help him build self-confidence.
Leo discovers three teen super-humans Adam, Bree and Chase, living in a secret underground lab in the high-tech home he shares with his inventor stepdad, Donald Davenport, his mom, Tasha, and Eddy, the "smart house" computer. Leo takes the trio to school, but when they are unable to contain their bionic abilities on campus, Davenport sends them away to a remote secret lab.
The trio has switched places with robot versions of themselves, sending the robots to the remote lab. Tasha is afraid of Leo's attachment to the 'robots' and convences Donald to send them to the scrap yard. Leo heads off to rescue his new friends. On their return home Donald agrees to let them stay and learn about normal human life if they and Leo can keep their bionic powers a secret.
On the Lab Rats' first day of school, all goes awry when Chase is confronted by a football player and his "Commando App" is triggered, transforming him into Spike, an unruly drill sergeant. When Spike defies the school principal, she pits the Lab Rats up against the football team to battle it out for the coveted cafeteria table
When Leo needs help asking a girl to the school dance, Adam and Chase step in to help, but the plan backfires when she falls for the wrong brother. The boys decide to settle their differences on the dance floor and each show off their best moves. Meanwhile, Bree gets to know her crush, but he gets to know her glitche
The Lab Rats get their first mission to stop Davenport's hi-tech super fast train from speeding out of control.
When Davenport's prized invention, a super strength and laser empowered exoskeleton suit, malfunctions, after Chase reverses its controls, to get back at Leo for stealing his presenting job. However, it ends up unleashing destructive power on the household, making Leo's grandma even more suspicious of the family.
When Chase refuses to admit that Adam has good ideas Adam decides to run against him for student of the semester. Meanwhile, Leo takes advantage of Bree's super speed and starts using her as his personal taxi.
When Adam, Bree and Chase forget to invite Leo to his surprise birthday party, they must make it up to him, so they take Leo into the ultra-cool virtual mission simulator and show him what it's like to be bionic.
Leo & Adam team up for the school fitness challenge expecting Adam's bionics to be his secret weapon; the plan backfires when they end up going head-to-head in the finals. Meanwhile, Bree and Chase use their bionic abilities against one another.
Leo borrows Davenport's helicopter to take Janelle on a daring date. Bree gets her own room and Adam and Chase are excited to have a room to themselves. But things get out of hand and Chase divides the room up.
Future Leo travels back in time to tell Leo, that Chase, Bree, and Adam won't make it to the future, and Leo is the only one who can save them.
Adam, Bree and Chase switch their bionics but things end up not the way they think when they can't handle it anymore.
Leo is left alone to care for the Lab Rats, but things quickly go wrong when he plays with a new gadget that glitches Adam, Bree, and Chase.
Adam, Bree and Chase learn about chores and earn allowance for the first time. To raise more money, they host a yard sale and accidentally sell an antique jewelry box that Davenport was restoring for Tasha.
Tasha takes the entire family on a nice 'tech free' beach weekend in the RV, but when Davenport discovers a solar flare headed in the Earth's direction, he secretly enlists the help of the Lab Rats.
In order to fight Trent's bullying, Leo signs up for a one-on-one basketball game against his rival.
When Leo accidentally messes up Eddy, an evil demon Teddy replaces him.
Adam, Bree, and Chase are caught on Principal Perry's surveillance camera using bionics.
Leo is blamed for breaking Marcus' guitar.
Chase accidentally discovers that he has a hidden ability - telekinesis.
